Pacific Research Network
Pacific Research Network (PRN) is a Southern California clinical research facility that specializes in examining new, investigational medications for the treatment of a variety of diseases.
With clinic locations in San Diego and Vista, California, Pacific Research Network has been a leader in the field of clinical research for over 35 years and is dedicated to providing quality research for both volunteers and the pharmaceutical industry.
Stephen G. Thein, PhD, the director and founder of Pacific Research Network, has conducted over 250 clinical trials and is one of the nation’s leading researchers in memory and Alzheimer’s disease. Dr. Thein has participated in the testing of several new medications to treat Alzheimer’s disease, memory loss, anxiety, migraine, sleep disorders, sexual dysfunction, smoking, social anxiety, and weight loss.
Over the past 30 years Pacific Research Network has made many contributions in the development of new medications to improve memory. Thousands of patients have been a part of our Memory Clinic’s approximate 300 grant-supported programs in various types of memory-loss of the mildest to the most severe. Additionally, over 5,000 people have chosen to take advantage of The Clinic’s unique 45-minute memory assessment.
Many have chosen to participate in a study that might protect memory function. Some of those who took the memory assessment chose to take the results to their own physician for review or treatment. In addition, many have allowed us to store their results at the clinic for a future memory assessment comparison. These results comprise our “data-banking” that allows for a “critical assessment of changes over time,” which allows for a detailed comparison that may identify insidious changes that might go undetected.
Stephen G. Thein, PhD
Director, has conducted over 250 clinical trials in the past 35 years. Dr. Thein is a clinical psychologist and received his PhD in professional psychology in 1974 and completed specialty training in neuropsychopharmacology at San Diego Neuropsychiatric Medical Clinic. He is recognized as a leading researcher and lecturer in CNS/Neurology. He is an active member of the ADCS and his work has been published in several peer-review journals, including the Journal of Clinical Psychiatry, Annals of Neurology, Neurology, and the Journal of the American Medical Association.
Jill E. Crusey, PhD
Jill E. Crusey, PhD became involved in the field of aging and memory while developing one of the first Older Adult programs in psychiatry at Northwestern University, Chicago, Illinois. Subsequently, her research and teaching efforts have focused on an aging population and the social, emotional, and physical consequences. Dr. Crusey has been affiliated with Pacific Research Network, Inc. for over twenty years, and during that time she has participated on over fifty trials related to dementia, Alzheimer’s, and other memory concerns.
Thomas J. Reilly, MD
Thomas J. Reilly, MD has come to the field of clinical research through his Vice Chairmanship of the Institutional Review Board of Biomedical Research Institute of America in San Diego, California. He has reviewed hundreds of protocols with a view to safety of participation for the subjects as well as the merits of the research protocol in general.
John J. Doria, MD
John J. Doria, MD is a well established member of the San Diego Family Medical community. He has worked with Pacific Research Network, Inc. since 1984, and was one of the founders of Sharp Rees-Stealy Family Practice Department, La Mesa. This licensed family practitioner and staff physician has served on many CNS trials as Sub-Investigator and Principal Investigator for the research site.
Daniel Lawler, MD
Daniel Lawler, MD is board certified in anesthesiology and has a certificate from the Clinical Trials Research and Design Program, University of California San Diego, San Diego, California. He has served as Sub-Investigator/staff physician since 2009 at Pacific Research Network. Dr. Lawler obtained his medical license from the Medical College of Wisconsin, Milwaukee, Wisconsin in 1990 and completed his residency at the University of Colorado Health Science Center, Denver, Colorado in 1994. Dr. Lawler continues to serve as Chair for the Department of Anesthesia, Colorado Plastic Surgery Center, Coronado, California, and Staff Anesthesiologist at the San Diego Out-Patient Surgery Center, San Diego California. He has worked on numerous CNS trials, predominantly infusion-related AD and MS studies those requiring single or repeated lumbar punctures.
Arthur M. Flippin, MD
Arthur M. Flippin, MD is a board-certified neurologist with over 20 years of practice in general neurology, caring for patients with a wide range of neurological conditions. In 1977 he joined the Department of Neurology at Kaiser Permanente in San Diego. From 1981-1999 he was privileged to serve as Chief of the Neurology Department. From 1998-2000 he served as Regional Coordinating Chief of Neurology for the Southern California Permanente Medical Group. He left clinical practice to move into a full-time administrative position as Area Medical Director for Southern California Permanente Medical Group in 2000 and remained there until his mandatory retirement at the end of 2009. He now serves as a Principal Investigator and Sub-Investigator with PRN on CNS trials requiring his professional expertise.