Pacific Research Network (PRN) is a Southern California clinical research facility that specializes in examining new, investigational medications for the treatment of a variety of diseases.

With clinic locations in San Diego and Vista, California, Pacific Research Network has been a leader in the field of clinical research for over 35 years and is dedicated to providing quality research for both volunteers and the pharmaceutical industry.

Stephen G. Thein, PhD, the director and founder of Pacific Research Network, has conducted over 250 clinical trials and is one of the nation’s leading researchers in memory and Alzheimer’s disease. Dr. Thein has participated in the testing of several new medications to treat Alzheimer’s disease, memory loss, anxiety, migraine, sleep disorders, sexual dysfunction, smoking, social anxiety, and weight loss.

  • Free Parking or Transportation
  • Comfortable Accommodations
  • Catered Meals
  • Recreational Facilities
  • Computer Access with Wi-Fi
  • Experienced, Friendly Staff


Over the past 30 years Pacific Research Network has made many contributions in the development of new medications to improve memory. Thousands of patients have been a part of our Memory Clinic’s approximate 300 grant-supported programs in various types of memory-loss of the mildest to the most severe. Additionally, over 5,000 people have chosen to take advantage of The Clinic’s unique 45-minute memory assessment. Many have chosen to participate in a study that might protect memory function. Some of those who took the memory assessment chose to take the results to their own physician for review or treatment. In addition, many have allowed us to store their results at the clinic for a future memory assessment comparison. These results comprise our “data-banking” that allows for a “critical assessment of changes over time,” which allows for a detailed comparison that may identify insidious changes that might go undetected.

Our Doctors

Stephen G. Thein, PhD

Director, has conducted over 250 clinical trials in the past 35 years. Dr. Thein is a clinical psychologist and received his PhD in professional psychology in 1974 and completed specialty training in neuropsychopharmacology at San Diego Neuropsychiatric Medical Clinic. He is recognized as a leading researcher and lecturer in CNS/Neurology. He is an active member of the ADCS and his work has been published in several peer-review journals, including the Journal of Clinical Psychiatry, Annals of Neurology, Neurology, and the Journal of the American Medical Association.

Dr. Thein is a member of the American Board of Psychological Specialties, American College of Forensic Examiners, American Psychological Association, Association for the Advancement of Psychology, the National Register, the American Academy of Sleep Medicine, and Prescribing Psychologists’ Register, and he is a fellow of the American College of Advanced Practice Psychologists.

Dr. Thein serves as consultant to the pharmaceutical industry including assisting with Alzheimer’s Disease (AD) protocol design, preparation of training videos/tools, and is a member of the advisory boards and has contributed to pharmaceutical training scales and publications of AD. He was also involved in the original development of the CIBIC(+) as a primary AD assessment tool.